| Date | Home | Away | Result |
|---|---|---|---|
| 13/09/25 15:30 | Ajax Amsterdam | PEC Zwolle | 3-1 |
| 13/09/25 17:45 | NEC Nijmwegen | PSV Eindhoven | 3-5 |
| 13/09/25 18:10 | Go Ahead Eagles Deventer | FC Volendam | 3-0 |
| 13/09/25 20:00 | FC Twente Enschede | NAC Breda | 2-2 |
| 13/09/25 20:00 | Feyenoord Rotterdam | SC Heerenveen | 1-0 |
| 14/09/25 11:15 | Excelsior Rotterdam | Sparta Rotterdam | --- |
| 14/09/25 13:30 | Heracles Almelo | AZ Alkmaar | --- |
| 14/09/25 13:30 | FC Utrecht | FC Groningen | --- |
| 14/09/25 15:45 | Telstar | Fortuna Sittard | --- |